Principal Clinical Scientist

About the Role

What if your career designing rigorous clinical trials and interpreting regulatory-grade data could directly shape how AI understands biomedical science? We're looking for a Principal Clinical Scientist to bring senior-level clinical expertise into the development of cutting-edge AI systems — ensuring these models reason about clinical evidence the way the world's top regulatory scientists do.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the frontier of AI and biomedical research.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
• Provide expert, structured feedback that shapes how AI models reason about clinical trial data, outcomes, and evidence
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing clinical trial protocols intended for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent bodies
• Strong command of clinical research methodology, biostatistics, or translational science
• Rigorous, detail-oriented thinker who can translate complex clinical concepts into clear, structured feedback
• Self-motivated and reliable when working independently without supervision

Nice to Have

• Prior experience with data annotation, data quality review, or AI evaluation workflows
• Background in regulatory affairs, medical writing, or clinical operations
• Familiarity with AI tools or machine learning applications in healthcare or life sciences
• Experience contributing to multi-site or global clinical trials

Why Join Us

• Work directly on frontier AI systems making an impact in clinical and biomedical research
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Collaborate with world-leading AI research teams and labs
• Potential for ongoing work and contract extension as new projects launch